SULFAMETHOXAZOLE; TRIMETHOPRIM or SMX-TMP is a combination of a sulfonamide antibiotic and a second antibiotic, trimethoprim. It is used to treat bacterial infections. It is also used to prevent infections in people who are at risk. It will not work for colds, flu, or other viral infections.
What should my health care professional know before I take this medicine?
They need to know if you have any of these conditions:
anemia
asthma
being treated with anticonvulsants
if you frequently drink alcohol containing drinks
kidney disease
liver disease
low level of folic acid or glucose-6-phosphate dehydrogenase
poor nutrition or malabsorption
porphyria
severe allergies
thyroid disorder
an unusual or allergic reaction to sulfamethoxazole, trimethoprim, sulfa drugs, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
How should I take this medicine?
Take this medicine by mouth with a full glass of water. Take your medicine at regular intervals. Do not take it more often than directed. Do not skip doses or stop your medicine early.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed. This medicine has been used in children as young as 2 months of age.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
What may interact with this medicine?
Do not take this medicine with any of the following:
aminobenzoate potassium
dofetilide
metronidazole
This medicine may also interact with the following:
ACE inhibitors like benazepril, enalapril, lisinopril, and ramipril
cyclosporine
digoxin
diuretics
indomethacin
medicines for diabetes
methenamine
methotrexate
phenytoin
potassium supplements
pyrimethamine
sulfinpyrazone
tricyclic antidepressants
warfarin
This list may not describe all possible interactions. Give your health care providers a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medicine?
Tell your doctor or health care professional if your symptoms do not improve. Drink several glasses of water a day to reduce the risk of kidney problems.
Do not treat diarrhea with over the counter products. Contact your doctor if you have diarrhea that lasts more than 2 days or if it is severe and watery.
This medicine can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use a sunscreen. Do not use sun lamps or tanning beds/booths.
What side effects may I notice from this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash or hives, swelling of the face, lips, or tongue
breathing problems
fever or chills, sore throat
irregular heartbeat, chest pain
joint or muscle pain
pain or difficulty passing urine
red pinpoint spots on skin
redness, blistering, peeling or loosening of the skin, including inside the mouth
unusual bleeding or bruising
unusually weak or tired
yellowing of the eyes or skin
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
diarrhea
dizziness
headache
loss of appetite
nausea, vomiting
nervousness
This list may not describe all possible side effects.
Where can I keep my medicine?
Keep out of the reach of children.
Store at room temperature between 20 to 25 degrees C (68 to 77 degrees F). Protect from light. Throw away any unused medicine after the expiration date.
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